Preheat oven to 350°F. Spray a 9 x 5-inch loaf pan with baking spray and line with parchment paper.
In a large mixing bowl, lightly beat together 2 large eggs and 1 cup sugar until just incorporated. Stir in 1 cup persimmon puree, ½ cup avocado oil, and ½ teaspoon vanilla extract and combine until oil is well incorporated.
In a large fine mesh sieve or sifter set over bowl with liquid ingredients, add 1¾ cup flour, 1 teaspoon baking soda, ½ teaspoon salt, 1 teaspoon cinnamon, and ½ teaspoon ground ginger. Tap sieve or sift dry ingredients directly into liquid ingredient in bowl.
Gently stir dry ingredients into liquid ingredients until dry ingredients are just incorporated. It's okay if there are a few small lumps throughout the batter. Fold in any optional mix-in ingredients like chocolate chunks, nuts, or dried fruit if using.
Pour Persimmon Bread batter into loaf pan. Gently tap against countertop to get rid of any large air bubbles. Top with 4-5 paper-thin slices of persimmon.
Bake for 50 minutes, or until a wooden tester comes out clean.